Usually initial dose makes 10 mg of 1 times/sut in the evening.
At easy or moderated гиперхолестеринемии the initial dose makes 5 mg/days
In need of application of higher doses dose increase should be made, observing 4-week intervals. The maximum daily dose - 80 mg.
If level LPNP falls below 75 mg/dl (1.94 mmol/l) or level of the general cholesterol of plasma falls below 140 mg/dl (3.6 mmol/l), it is necessary to reduce dose
zocor
.At IBS zocor appoint in an initial dose of 1 times/sut of 20 mg in the evening. Correction of a mode of dispensing, in case of need, should be carried out the same as and Hypercholesterolaemia. At the patients receiving Cyclosporin,FIBRATE,nicotinic acid together with zocor, the maximum recommended dose makes 10 mg/days
As zocor it is deduced by kidneys in a small amount, there is no necessity for change of a dose at patients with moderately expressed infringements of function of kidneys. At patients with the expressed infringements of function of kidneys (a road clearance Creatinine less than 30 ml/mines) should be estimated carefully expediency of appointment of a preparation in a dose exceeding 10 mg/days If such dose is considered necessary, it is necessary to appoint it with care.
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